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Mrs Chrystalla Pavlou, BSc(Hons), MSc
Postgraduate Researcher Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id esLorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborums.
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Dr Marina Demetriades, BSc(Hons), Ph.D
Post-Doctoral Researcher Dr Demetriades obtained her BSc(Hons) from the Department of Chemistry at the University of Cyprus in 2009, working in synthetic organic chemistry with Prof Koutentis. She then received a scholarship at the University of Oxford (UK) where she worked on Dynamic Combinational Mass Spectrometry at Prof Schofield lab, for which she was awarded with a PhD in Organic Chemistry in 2013. Marina worked at the University of Oxford in various roles (Junior Laboratory Demonstrator, Exams Invigilator, Teaching Assistant and Post-Doctoral Research Assistant) gaining valuable teaching and research experience. She then joined the laboratory of Prof Barr at the University of Oxford, Department of Biochemistry, where she worked for three years on phosphoprotein phosphatases as potential cancer targets. Dr Demetriades joined UCY and the Experimental Pharmacology Laboratory in Sep 2017 after being successful in a competitive internal post-doctoral funding program.
At Experimental Pharmacology Laboratory, Dr Demetriades aims to set-up the "University of Cyprus Drug Library" and develop a number of in vitro assays for cancer target screening. Marina's multidisciplinary laboratory experience (e.g. organic synthesis, spectroscopy, SAR studies, in vitro assay development) provides a solid base for the Lab's development towards achieving its ambitious aims. |
Lab Interns
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Mr Antonis Pylavas
(Med student, MD Year 3) 
Antonis is working on toxicity screenings of various drugs, using zebrafish larvae. He records the grade of lethality of clinical compounds in zebrafish larvae. "Zebrafish are a very useful organism in toxicity testing, but not many compounds have been screened in this organism in order to correlate accuratey its toxicity profile with rodents and humans." |
Mrs Melani Theodoridou
(Med student, MD Year 3) 
Melani is working on recording main toxicological parameters of letahlity of compounds and validating an optimum toxicity protocol for the characterisation of drugs and compounds. "The toxicity profile of drugs in zebrafish larvae can vary greatly based on a number of parameters, apart from drug exposure time and concentration. It is important that these parameters be determined accurately and their impact on toxicity profiling evaluated". |
Mr Nikos Ververides
(Med student, MD Year 3) 
Nikos is interested in the discovery of drugs that have anticancer activity. He screens novel compounds and clinical drugs for anticancer efficacy against various cancer types using different assays that evaluate cell survival and proliferation. "Although many anticancer drugs are used in the clinic today, there are still a number of cancers that are resistant to treatment. New drugs are needed to develop new treatments and improve the survival of cancer patients." |
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Mr Argyris Constantinou
(Med student, MD Year 3) 
Argyris is works in the antibacterial screening of compounds using the microdilution growth inhibition assay. He uses this assay in clinical drug screening against pathological bacteria. "The microdilution growth inhibition assay offers a high-throughput system for screening drugs with antibacterial activity and its one of the best assays for quick screening of compounds". |
Mr Charalambos Anagnostopoulos
(Med student, MD Year 2) 
Charalambos is interested in the synergistic effect of compounds when in combination with antibiotics, using versions of the disc dilution assay. "The disc diffusion assay is a very useful assay to screen for synergy of drug combinations, as the only parameter that matters in the assay is drug concentration. Synergy is key in modern anti-infection strategies in the clinic." |
Mrs Christina Pasiouli
(Med student, MD Year 2) 
Christina is interested in the exploration of the bacteriostatic properties of clinical drugs as part of a drug repurposing screening. "The bacteriostatic activity of drugs is very important in our understanding of bacterial life and can help us discover new molecular targets that can help in our fight against infections." |
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Mr Petros Pieri
(Med student, MD Year 2) 
Christina is interested in the exploration of the bacteriostatic properties of clinical drugs as part of a drug repurposing screening. She uses the colony forming assay conditions to screen for drugs that inhibit bacteria proliferation and colony formation. "The bacteriostatic activity of drugs is very important in our understanding of bacterial life and can help us discover new molecular targets that can help in our fight against infections." |
Mrs Marina Evaggelou
(Med student, MD Year 2) 
Christina is interested in the exploration of the bacteriostatic properties of clinical drugs as part of a drug repurposing screening. She uses the colony forming assay conditions to screen for drugs that inhibit bacteria proliferation and colony formation. "The bacteriostatic activity of drugs is very important in our understanding of bacterial life and can help us discover new molecular targets that can help in our fight against infections." |
Mrs Sofia Filipou
(Med student, MD Year 2) 
Christina is interested in the exploration of the bacteriostatic properties of clinical drugs as part of a drug repurposing screening. She uses the colony forming assay conditions to screen for drugs that inhibit bacteria proliferation and colony formation. |
